Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypoxia
ADR ID BADD_A02233
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.02      Conditions associated with abnormal gas exchange
22.02.02.003      Hypoxia
Description A disorder characterized by a decrease in the level of oxygen in the body. [CTCAE] Sub-optimal OXYGEN levels in the ambient air of living organisms. | Relatively complete absence of oxygen in one or more tissues. [MeSH]
MedDRA Code 10021143
MeSH ID D000860; D000860; D000860
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Alveolar aeration decreased | Hypoxaemia | Hypoxemia | Hypoxia | Hypoxic | Oxygen Deficiency | Deficiency, Oxygen | Deficiencies, Oxygen | Oxygen Deficiencies | Anoxia | Anoxemia
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
CCAAT/enhancer-binding protein epsilonQ6PZD9Not Available
NADH-cytochrome b5 reductase 3P00387Not Available
NADPH--cytochrome P450 reductaseP16435T95446
Sulfotransferase 1B1O43704Not Available
Sulfotransferase 1B1P52847Not Available
UDP-glucuronosyltransferase 2B15P54855Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01167Interferon alfa-2b--
BADD_D01182Iopromide--
BADD_D01186Ioversol--
BADD_D01191Ipratropium0.000225%
BADD_D01199Iron sucrose0.003332%
BADD_D01221Ivermectin0.001739%
BADD_D01222Ixabepilone--
BADD_D01228Ketamine0.004335%
BADD_D01230Ketoconazole0.000329%
BADD_D01242Lamivudine--
BADD_D01243Lamotrigine--
BADD_D01245Lansoprazole0.000328%
BADD_D01252Leflunomide0.003098%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib--
BADD_D01258Leucovorin0.005831%
BADD_D01265Levetiracetam--
BADD_D01275Levofloxacin--
BADD_D01282Levorphanol--
BADD_D01285Levothyroxine--
BADD_D01295Linezolid--
BADD_D01300Lisinopril0.000198%
BADD_D01318Lorazepam0.000738%
BADD_D01322Losartan--
BADD_D01336Macitentan0.019053%
BADD_D01349Mannitol--
BADD_D01378Memantine0.001441%
BADD_D01393Meropenem0.000056%
BADD_D01401Metformin--
BADD_D01405Methadone0.002431%
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